Does Riedel thyroiditis cause hypothyroidism?
Does Riedel thyroiditis cause hypothyroidism?
Riedel fibrosing thyroiditis is a rare disease characterized by chronic inflammation and fibrosis of the thyroid gland. It is also known as Riedel struma, ligneous struma, or chronic invasive fibrous thyroiditis. [1] Classically, it presents as hypothyroidism with a “stone-like, hard-as-wood” non-tender thyroid gland.
Is Riedel’s thyroiditis an autoimmune disease?
It is believed to be an autoimmune condition, where the immune system attacks normal tissue. It is sometimes called Riedel’s struma or invasive fibrous thyroiditis. Riedel’s thyroiditis is more common in women than in men, and generally affects people between the ages of 30 and 60.
What is painless thyroiditis?
Painless thyroiditis is characterized by transient hyperthyroidism, followed sometimes by hypothyroidism, and then recovery (figure 1). Synonyms for this disorder include silent thyroiditis, subacute lymphocytic thyroiditis, and lymphocytic thyroiditis with spontaneously resolving hyperthyroidism.
What does thyroiditis pain feel like?
Subacute thyroiditis: Mild to severe pain in the thyroid gland. The thyroid feels tender to the touch. Pain or discomfort when swallowing or turning your head. Appearance of these symptoms shortly after a viral infection, such as the flu, mumps, or measles.
What do you need to know about Riedel’s thyroiditis?
Riedel’s thyroiditis is a fibrotic process of the thyroid gland which characteristically extends through adjacent tissues generating gland destruction, infiltration in cervical structures and even air way obstruction.
Which is rare Hashimoto’s or Riedel’s thyroiditis?
Riedel’s thyroiditis is exceedingly rare, occurring in some series one 50th as frequently as Hashimoto’s thyroiditis (11–15). There is a paucity of robust epidemiological data because the world’s literature consists primarily of case reports and small case series.
How is tamoxifen used to treat Riedel’s thyroiditis?
Our studies suggest that this is unrelated to antiestrogen activity. Tamoxifen’s effectiveness may be caused by a mechanism by which it stimulates the release of transforming growth factor-β, which may inhibit the fibroblastic proliferation characteristic of Riedel’s thyroiditis.
What makes the thyroid gland hard and Woody?
This makes the thyroid gland stone-hard (woody) and fixed to adjacent structures. The inflammatory process infiltrates muscles and causes symptoms of tracheal compression.