What is a metanephrines plasma test for?
What is a metanephrines plasma test for?
The plasma free metanephrines test is used to help diagnose or rule out the presence of a rare tumor called a pheochromocytoma or a paraganglioma (PPGL) that releases excess metanephrines. Testing also may be used when a tumor has been treated or removed to monitor for recurrence.
What does high levels of metanephrines mean?
Higher levels of metanephrines may mean that you have an adrenal gland tumor. But false-positive results can happen. Higher levels may also be caused by obstructive sleep apnea, stress, or other illnesses.
How long does metanephrines plasma test results take?
Turnaround for this test is typically 8-10 business days. Requirements: Avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection. Overnight fasting is preferred.
What causes low metanephrines in urine?
To help diagnose or rule out a rare tumor of the adrenal gland called a pheochromocytoma or a rare tumor outside the adrenal glands called a paraganglioma; these tumors (PPGL) produce excess catecholamines, which are broken down to metanephrines.
Is plasma metanephrines a blood test?
Your doctor has recommended that you have a blood test for plasma metanephrines. This is a simple blood test to identify the level of these hormones in your blood.
What is the normal level of Metanephrines urine?
Metanephrine: 24 to 96 mcg/24 hours (some laboratories give the range as 140 to 785 mcg/24 hours) Norepinephrine: 15 to 80 mcg/24 hours (89 to 473 nmol/24 hours)
When to use plasma or urinary fractionated metanephrines?
Both plasma metanephrines and plasma catecholamines have been used for the diagnosis of pheochromocytoma. If plasma metanephrines and/or catecholamines are not available, then the next best test is urinary fractionated metanephrines and/or catecholamines.
What is the CPT for plasma free metanephrines?
Metanephrines, Fractionated, Plasma Free TEST: 121806 CPT: 83835
When to use 24 hour fractionated metanephrines?
The 24-hour urinary fractionated metanephrines (a more specific assay) may be used as the first test for low suspicion cases and also as a confirmatory study in patients with a less than 2-fold elevation in plasma free fractionated metanephrines.
Which is the second line test for metanephrines?
(3) The recommended second-line test is measurement of fractionated 24-hour urinary metanephrines (METAF / Metanephrines, Fractionated, 24 Hour, Urine). In most cases this strategy will suffice in confirming or excluding the diagnosis.