Can high B12 cause anemia?
Can high B12 cause anemia?
A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.
Is B12 related to iron deficiency?
Commonly, vitamin B12 deficiency is associated with macrocytic anemia. However, the patient’s mean corpuscular volume (MCV) was normal which suggested the presence of concomitant iron deficiency anemia. Increased RDW was consistent with poikilocytosis and anisocytosis picture in the peripheral blood smear.
Why would B12 levels be high?
Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)
What happens when B12 is too high?
It is, however, important to note that too much B12 may cause issues in certain cases. In some people, high levels of B12 may cause gastrointestinal problems such as bloating and diarrhea. And if you have high blood pressure or poor cardiovascular health, having too much B12 may further complicate these issues.
What causes elevated B12 levels?
According to the Mayo Clinic, “Vitamin B12, or cobalamin, helps nerve cells, red blood cells and is used in the creation of DNA.”. Over-production of Vitamin B12 can be caused by cirrhosis, hepatitis, polycythemia vera or myelocytic leukemia. Vitamin B12 supplements will not cause elevated B12 blood levels.
What does an elevated B12 level mean?
Elevated levels of B12 can be caused by cirrhosis, scarring of the liver. Decreased liver function corresponds to elevated B12 levels because the liver cannot maintain B12 properly and the remainder is dispersed throughout the body.
What does high B12 blood levels really mean?
High blood B12 levels can occur in liver conditions such as cirrhosis and hepatitis. Alcoholic liver disease is an example of a liver condition associated with high vitamin B12 . With alcoholic liver disease, vitamin B12 as well as its carrier proteins can be elevated.