What is the use of papaverine?
What is the use of papaverine?
Papaverine is used to improve blood flow in patients with circulation problems. It works by relaxing the blood vessels so that blood can flow more easily to the heart and through the body. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Does papaverine help with pain?
Papaverine is used to treat many conditions that cause spasm of smooth muscle. This includes chest pain, circulation problems, heart attack, or disorders of the stomach or gallbladder.
What is the action of papaverine?
The main actions of papaverine are exerted on cardiac and smooth muscle. Like quinidine, papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists.
What is the generic name for papaverine?
BRAND NAME(S): Pavabid. USES: This medication is used to increase blood flow throughout the body, including the heart and the brain. Papaverine is a vasodilator. It works by relaxing the muscles in the blood vessels.
How long does papaverine last?
lasts for more than four hours. Patients should be instructed to seek medical help immediately if they have self-administered an overdose of papaverine hydrochloride.
What type of drug is papaverine?
PAPAVERINE (pa PAV er een) is a vasodilator. It relaxes the blood vessels which makes it easier for blood to pass through them. It is used to treat certain conditions that cause blood vessels to spasm. This medicine may also be used to relieve the spasms associated with urinary tract, gallbladder or stomach.
What type of antagonist is papaverine?
Papaverine is an inhibitor of PDE enzyme leading to increase cGMP in penile tissue. The major disadvantage of papaverine is corporal fibrozis thought to be a result of low acidity. Phentolamine is an α-receptor antagonist that increases blood flow. Systemic hypotension and tachycardia are its major adverse effects.
What kind of medication is papaverine?
Papaverine belongs to the group of medicines called vasodilators. Vasodilators cause blood vessels to expand, thereby increasing blood flow. Papaverine is used to produce erections in some men with erectile dysfunction.
Are there preservatives in papaverine hydrochloride injection?
The 10 mL vials also contain chlorobutanol 0.5% as a preservative. pH may be adjusted with sodium citrate and/or citric acid. The most characteristic effect of papaverine is relaxation of the tonus of all smooth muscle, especially when it has been spasmodically contracted.
Are there any side effects to taking papaverine?
papaverine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of papaverine. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
How long does it take to take papaverine?
Papaverine is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection. When injected into a vein, papaverine must be given slowly (over 1 or 2 minutes) to prevent vein irritation or other side effects.
How does papaverine hydrochloride work on smooth muscle?
The most characteristic effect of papaverine is relaxation of the tonus of all smooth muscle, especially when it has been spasmodically contracted. Papaverine Hydrochloride apparently acts directly on the muscle itself.
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