What is mesna used for?
What is mesna used for?
Mesna is used to reduce the risk of hemorrhagic cystitis (a condition that causes inflammation of the bladder and can result in serious bleeding) in people who receive ifosfamide (a medication used for the treatment of cancer). Mesna is in a class of medications called cytoprotectants.
How is mesna given?
Where ifosfamide or cyclophosphamide is used as an iv bolus: Mesna is given by intravenous injection over 15-30 minutes at 20% of the simultaneously administered oxazaphosphorine on a weight for weight basis (w/w). The same dose of mesna is repeated after 4 and 8 hours.
How long does mesna stay in system?
Excretion. Following intravenous administration of a single 800 mg dose, approximately 32% and 33% of the administered dose was eliminated in the urine in 24 hours as mesna and dimesna, respectively. Mean plasma elimination half-lives of mesna and dimesna are 0.36 hours and 1.17 hours, respectively.
How much does mesna cost?
The cost for mesna injectable solution (100 mg/mL) is around $26 for a supply of 10 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Is Mesna a chemotherapy?
Mesna is a drug given with some types of chemotherapy to help protect the bladder from irritation.
Is Mesna effective?
A total of 68 cycles of cyclophosphamide were given with mesna, with a median of three cycles per patient. A recurrence of cystitis was prevented in all but one patient. Thus, mesna is effective in preventing recurrent cystitis in patients receiving further cyclophosphamide.
Is mesna effective?
What does mesna stand for?
mesna
| Synonym: | mercaptoethane sulfonate Mesnum |
|---|---|
| Foreign brand name: | Ausobronc Filesna Mesnil Mexan Mistabron Mistabronco Mitexan Mucofluid Mucolene Uromitexan Ziken |
| Abbreviation: | MSA |
| Code name: | D-7093 UCB 3983 |
| Chemical structure: | 2-mercaptoethanesulfonic acid, sodium salt sodium 2-mercaptoethane sulfonate |
What does Mesna stand for?
Is mesna a chemotherapy?
Is mesna hazardous?
Hazard Statements: Causes serious eye damage. Causes severe skin burns and eye damage. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Is Mesna hazardous?
Are there any side effects to Mesnex 400 mg tablets?
MESNEX tablets: 400 mg film-coated tablets with functional score Mesna is contraindicated in patients known to be hypersensitive to Mesna or to any of the excipients [see Warnings and Precautions (5.1) ]. Mesna may cause systemic hypersensitivity reactions, including anaphylaxis.
What do you need to know about mesna injections?
Mesna Description. MESNEX (Mesna) injection is a sterile, nonpyrogenic, aqueous solution of clear and colorless appearance in clear glass multidose vials for intravenous administration. MESNEX injection contains 100 mg/mL Mesna, 0.25 mg/mL edetate disodium and sodium hydroxide for pH adjustment.
How much benzyl alcohol is in a mesna injection?
Mesna injection contains 100 mg/mL Mesna, 0.25 mg/mL edetate disodium and sodium hydroxide for pH adjustment. Mesna injection multidose vials also contain 10.4 mg/mL of benzyl alcohol as a preservative. The solution has a pH range of 7.5-8.5.
What is the molecular formula for the drug mesna?
Mesna is a detoxifying agent to inhibit the hemorrhagic cystitis induced by ifosfamide. The active ingredient, Mesna, is a synthetic sulfhydryl compound designated as sodium-2-mercaptoethane sulfonate with a molecular formula of C2H5NaO3S2 and a molecular weight of 164.18.