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What is Zometa used to treat?

What is Zometa used to treat?

Zoledronic acid (Reclast) is also used to treat Paget’s disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Zoledronic acid (Zometa) is used to treat high levels of calcium in the blood that may be caused by certain types of cancer.

Are bisphosphonates used to treat multiple myeloma?

Background: Bisphosphonates are specific inhibitors of osteoclastic activity and are used in the treatment of patients with multiple myeloma (MM). While bisphosphonates are shown to be effective in reducing vertebral fractures and pain, their role in improving overall survival (OS) remains unclear.

What are the side effects of Zometa infusion?

Common side effects of Zometa include:

  • dizziness,
  • headache, or.
  • flu-like symptoms (such as fever, chills, muscle/joint aches),
  • cough,
  • vision problems,
  • diarrhea,
  • constipation,
  • tired feeling,

Which medicine is best for multiple myeloma?

The drugs used most often for treating bone problems in people with myeloma are the bisphosphonates pamidronate (Aredia) and zoledronic acid (Zometa) and the drug denosumab (Xgeva, Prolia). These drugs are given intravenously (IV or into a vein) or subcutaneously (under the skin).

What does Zometa do to your body?

Zoledronic acid belongs to a class of drugs known as bisphosphonates. It lowers high blood calcium levels by reducing the amount of calcium released from your bones into your blood. It also works by slowing the breakdown of your bones by cancer to prevent bone fractures.

Does Zometa affect your teeth?

A dental condition called jaw osteonecrosis has been reported in some patients being treated with Zometa or with other drugs in the same class as Zometa. You may need to have dental treatments completed before starting it.

What does Zometa do for multiple myeloma?

Patients with multiple myeloma have increased numbers of abnormal plasma cells that may produce increased quantities of dysfunctional antibodies detectable in the blood and/or urine. Zometa is a bisphosphonate drug that is commonly used to reduce the risk of bone complications from bone metastases or multiple myeloma.

How does multiple myeloma cause osteoporosis?

It occurs in most people with myeloma. Bone pain is a common symptom. Myeloma cells grow in the bone marrow and cortical bone, causing local bone damage or generalized thinning of the bone, which is called osteoporosis. This makes the bone more likely to break.

How long can you take Zometa?

Zoledronic acid is only part of a complete program of treatment that may also include diet changes and taking calcium and vitamin supplements. Follow your doctor’s instructions very closely. Your doctor will determine how long to treat you with this medicine. Zoledronic acid is often given for only 3 to 5 years.

How do steroids help multiple myeloma?

Myeloma Treatment and Dex Dexamethasone and the other steroids are useful in myeloma treatment because they can stop white blood cells from traveling to areas where cancerous myeloma cells are causing damage. This decreases the amount of swelling or inflammation in those areas and relieves associated pain and pressure.

When should I stop taking Zometa?

A robust fracture benefit is observed for three years of use, a more modest benefit for six vs three years, and inconclusive benefits for nine vs six years of continued use. The authors recommend that almost all patients who receive zoledronic acid can probably stop and expect benefit for up to three additional years.

Is Zometa a chemo drug?

Zoledronic acid (Zometa) is not cancer chemotherapy, and it will not slow or stop the spread of cancer. However, it can be used to treat bone disease in patients who have cancer. Zoledronic acid is in a class of medications called bisphosphonates . It works by slowing bone breakdown,…

What is Zometa treatment?

Zometa is used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). Zometa also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body.

How can chemotherapy drugs help treat multiple myeloma?

How can chemotherapy drugs help treat multiple myeloma? Chemotherapy is treatment with cancer-fighting drugs . Because these medicines go in your bloodstream and can reach all parts of your body, they’re a good choice to destroy myeloma cells. They can be injected into a vein or taken as pills.