What is suspension advantages and disadvantages?
What is suspension advantages and disadvantages?
Suspensions possess certain advantages over other dosage forms. Suspensions also possess some disadvantages relative to other dosage forms. The primary disadvantage is their physical instability; i.e., that they tend to settle over time leading to a lack of uniformity of dose.
What is the advantage of suspension?
The advantages of suspension dosage forms include effective dispensing of hydrophobic drugs; avoidance of the use of cosolvents; masking of unpleasant taste of certain ingredients; offering resistance to degradation of drugs due to hydrolysis, oxidation or microbial activity; easy swallowing for young or elderly …
What are the features of flocculated suspension?
INTRODUCTION
| Flocculated suspension | Deflocculated suspension |
|---|---|
| The rate of sedimentation is high. | The rate of sedimentation is slow. |
| Sediment is easy to re-disperse. | Sediment is difficult to re-disperse. |
| Sediment is loosely packed and does not form a hard cake. | Sediment is tightly packed and forms a hard cake. |
What is a flocculated suspension?
Flocculation is a process whereby small particles in suspension are caused to aggregate, giving large clusters (flocs) that are much more easily separated than the original particles. The process is in widespread use in many industrial applications.
What are the reasons for preparing suspensions?
The reasons for the formulation of a pharmaceutical suspension: — when the drug is insoluble in the delivery vehicle. –To mask the bitter taste of the drug. –To increase drug stability.
What are the disadvantages of syrup?
It contains much more toxic matter than sugar does. This syrup deteriorates the hormone balance in body. It is very hard takes long time to heal the deteriorated hormone balance. It leads an increase in hairiness.
What are the advantages of suspension type insulators?
Suspension insulators are cheaper in cost compared to pin type insulators for operating voltage above 50kV. Each unit of suspension insulators (insulator disc) is designed for comparatively low voltage (11kV) and can be increase the insulation strength by connecting these insulator disc modules in series.
What is the reason why we need to formulate suspension?
What is the difference between flocculated and non flocculated suspension?
The suspension are said to be flocculated ,when the individual particles are in contact with each other and form a network like structure . Whereas in case of non-flocculated suspensions,the individual particles exists as a separate entity. In Non-flocculated suspensions The rate of sedimentation is slow.
What is suspension medication used for?
This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever.
Why are suspensions used in medicine?
Substances can be chemically unstable, insoluble in water, distasteful etc. Suspensions are often used as a dosage form when the drug is insoluble in water and when use of solubilizing agents is not possible.
What are advantages of liquids?
Advantages of liquid fuels : They possess higher calorific value per unit mass than solid fuels. They burn without forming dust, ash, clinkers etc. Their firing is easier and also fire can be extinguished easily by stopping the liquid fuel supply. They are easy to transport through pipes.
How are deflocculated suspensions different from flocculated suspensions?
Deflocculated suspensions Whether a suspension is flocculated or deflocculated depends on the relative magnitudes of the electrostatic forces of repulsion and the forces of attraction between the particles. At low electrolyte concentration, the electrical repulsive force predominates and particle interactions are maximized.
What are the advantages of a stable floc?
Good pharmaceutical suspensions are best achieved through the formation of a stable floc, which resists the tendency toward either deflocculation or agglomeration. The chief advantages of the stable floc are as follows – The aggregates tend to break up easily under the application of small amounts of shear stress,…
What are the advantages and disadvantages of pharmaceutical suspensions?
3. Pharmaceutical suspensions may serve as an alternative means used to administer drugs to children including paediatric and geriatric patients and older patients who have difficulty swallowing solid dosage forms. 4. Drug in suspension exhibits higher rate of bioavailability than other dosage forms.
Why do flocculated suspensions form high sediment height?
In this suspension type, the structure of the aggregates is quite rigid; hence they settle quickly to form a high sediment height and are easily redispersible because the particles constituting individual aggregates are sufficiently far apart from one another to preclude caking.
