How does dengue fever affect the liver?
How does dengue fever affect the liver?
“Dengue virus attacks the cells that cause inflammation in the liver. The Alanine Aminotransferase (ALT) and Amino Alanine Transferase (AST) enzymes increase in number in the blood during the time and may cause complications including damage to liver,“ infectious diseases and internal medicine expert Mahesh Lakhe said.
Does dengue increase liver enzymes?
Infection with dengue can cause acute, febrile illness or severe disease, which can lead to plasma leakage, bleeding, and organ impairment. One of the most prominent clinical characteristics of dengue patients is increased aspartate and alanine aminotransferase liver enzyme levels.
Does dengue affect SGPT?
Liver involvement is one of the common features in dengue fever. Various studies have shown that in all those patients who develop complications like dengue hemorrhagic fever, dengue shock syndrome the levels of SGOT and SGPT were significantly raised.
What are the main organs involved in dengue hemorrhagic fever?
The liver as a target of immune-mediated mechanisms in dengue fatal cases. The liver is considered as an important target for DENV infection and is the most common organ to be involved in the disease.
Are there long term effects from dengue fever?
Dengue leaves some long term ill effects including hair fall, alopecia, joint pain and muscle pain. As per a study which was published in April 2013 edition of Nature, around 390 million people are infected with dengue virus every year, globally.
What causes liver enlargement in dengue?
Mechanisms of liver injury in dengue may be due to direct effects of the virus or host immune response on liver cells, circulatory compromise, metabolic acidosis and/or hypoxia caused by hypotension or localized vascular leakage inside the liver [5, 7, 10, 14, 22].
Can dengue cause fatty liver?
Nonalcoholic fatty liver disease is associated with increased hemoconcentration, thrombocytopenia, and longer hospital stay in dengue-infected patients with plasma leakage.
Which body part is affected by dengue?
During its journey, the dengue virus infects more cells, including those in the lymph nodes and bone marrow, macrophages in both the spleen and liver, and monocytes in the blood. The spread and increase of the virus results in viremia, a condition in which there is a high level of dengue virus in the bloodstream.
Can you fully recover from dengue?
Symptoms of dengue typically last 2–7 days. Most people will recover after about a week.