How is subacute sclerosing panencephalitis diagnosed?
How is subacute sclerosing panencephalitis diagnosed?
The diagnosis of subacute sclerosing panencephalitis may be confirmed by clinical evaluation and blood testing that reveals abnormally high levels of the measles antibody. Examination of the electrical activity of the brain (EEG) usually shows a characteristic pattern.
What is subacute sclerosing panencephalitis?
Subacute sclerosing panencephalitis (SSPE) is a progressive, disabling, and deadly brain disorder related to measles (rubeola) infection. The disease develops many years after the measles infection.
Does measles affect the brain?
About 1 child out of every 1,000 who get measles will develop encephalitis (swelling of the brain) that can lead to convulsions and can leave the child deaf or with intellectual disability. Death.
What is subacute disease?
A disease in which symptoms are less pronounced but more prolonged than in an acute disease, intermediate between acute and chronic disease.
What is subacute sclerosing panencephalitis SSPE )? symptoms causes?
Subacute Sclerosing Panencephalitis (SSPE)
- Subacute sclerosing panencephalitis is caused by the measles virus.
- The first symptoms are usually poor school performance, forgetfulness, temper outbursts, distractibility, sleeplessness, and hallucinations.
- The diagnosis is based on symptoms.
- This disorder is usually fatal.
Can measles cause mental illness?
This is a rare condition that can develop years after natural measles infection. SSPE is a degenerative neurological condition which progressively destroys nerve cells in the brain and almost always leads to mental deterioration and death.
How is SSPE treated?
How is SSPE treated? No cure is available for SSPE. However, your doctor can prescribe some antiviral drugs that may slow the progression of your condition. They may also prescribe anticonvulsant drugs to control seizures.
What do you need to know about subacute sclerosing panencephalitis?
Encephalitis and meningitis information page compiled by the National Institute of Neurological Disorders and Stroke (NINDS). Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of children and young adults that affects the central nervous system (CNS).
How is SSPE similar to other chronic viral infections?
Histopathologically, SSPE demonstrates the same changes seen in other chronic viral cerebral infections, such as HIV encephalitis and post-infectious encephalomyelitis 2. CSF analysis may show elevated levels of: Features depend on the stage of disease.
Is there a higher incidence of SSPE in males?
There is a higher incidence among males than females (male/female: 3/1). Most youngsters with SSPE have a history of measles infection at an early age, usually younger than 2 years, followed by a latent period of 6 to 8 years before neurological symptoms be…
Where is white matter involved in panencephalitis?
In the acute setting, patchy asymmetric regions of white matter involvement are present, typically in the temporal and parietal lobes. Mild reduction in grey matter involving predominately the amygdala, frontotemporal cortex, and cingulate gyrus can also be seen in the early stage of the disease 7.
