Is it safe to take 80 mg of pantoprazole a day?
Is it safe to take 80 mg of pantoprazole a day?
With doses above 80 mg daily, the dose should be divided and given twice daily. A temporary increase of the dose above 160 mg pantoprazole is possible but should not be applied longer than required for adequate acid control.
Can I cut pantoprazole 40 mg in half?
Swallow the tablets whole; do not split, chew, or crush them. If your doctor has prescribed the 40 mg tablet and it is too big for you to swallow, ask your doctor to prescribe two of the 20 mg tablets instead.
How much pantoprazole is lethal?
Single oral doses of pantoprazole at 709 mg/kg, 798 mg/kg, and 887 mg/kg were lethal to mice, rats, and dogs, respectively. The symptoms of acute toxicity were hypoactivity, ataxia, hunched sitting, limb-splay, lateral position, segregation, absence of ear reflex, and tremor.
What will happen if I take 2 pantoprazole?
People who are taking multiple daily doses of proton pump inhibitor medicines for a long period of time may have an increased risk of fractures of the hip, wrist or spine. Tell your doctor about any side effects that bother you or that do not go away. These are not all the possible side effects with pantoprazole.
How long can you take 80 mg of pantoprazole?
Pantoprazole is usually given for up to 8 weeks at a time while your esophagus heals. Pantoprazole is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid.
How many hours does pantoprazole last?
Pantoprazole is extensively metabolized in the liver through the cytochrome P-450 system, predominantly by CYP2C19 demethylation with subsequent sulfation and has a serum elimination half-life of about 1.1 hours.
How quickly does pantoprazole work?
When will I feel better? You should start to feel better within 2 to 3 days. It may take up to 4 weeks for pantoprazole to work properly so you may still have some symptoms during this time. If you bought pantoprazole without a prescription, and feel no better after 2 weeks, tell your doctor.
What is the generic name for pantoprazole 40 mg?
Generic Name: pantoprazole Pill with imprint PROTONIX is Yellow, Elliptical / Oval and has been identified as Protonix 40 mg. Protonix is used in the treatment of barrett’s esophagus; gerd; duodenal ulcer; erosive esophagitis; helicobacter pylori infection (and more), and belongs to the drug class proton pump inhibitors.
How many mg of pantoprazole can you take in one day?
If patients are unable to swallow a 40 mg tablet, two 20 mg tablets may be taken. Concomitant administration of antacids does not affect the absorption of pantoprazole sodium delayed-release tablets.
Are there any side effects of pantoprazole in humans?
In long-term rodent studies, pantoprazole was carcinogenic and caused rare types of gastrointestinal tumors. The relevance of these findings to tumor development in humans is unknown [see Nonclinical Toxicology (13.1)]. See Drug Interactions (7.5).
How often can you take pantoprazole for Zollinger Ellison?
Usual Adult Dose for Zollinger-Ellison Syndrome: Oral: 40 mg twice daily, to a maximum of 240 mg per day. Some patients have received treatment with pantoprazole for more than 2 years.