What are the side effects of thiazolidinedione?
What are the side effects of thiazolidinedione?
Side effects of glitazones may include:
- water retention.
- weight gain.
- eyesight problems.
- reduced sense of touch.
- chest pain and infections.
- allergic skin reactions.
Which of the following is a side effect of sulfonylureas?
Side effects of sulfonylureas may include:
- Signs of low blood sugar, such as sweating, dizziness, confusion, or nervousness.
- Hunger.
- Weight gain.
- Skin reactions.
- Upset stomach.
- Dark-colored urine.
What are the side effects of acarbose?
SIDE EFFECTS: Diarrhea, gas, upset stomach, constipation, or stomach pain may occur in the first few weeks of treatment as your body adjusts to this medication but usually improve with time….Common side effects may include:
- stomach discomfort, gas, bloating;
- mild diarrhea; or.
- mild skin rash or itching.
What is the side effect of pioglitazone?
Commonly reported side effects of pioglitazone include: upper respiratory tract infection, edema, and hypoglycemia. Other side effects include: cardiac failure, exacerbation of congestive heart failure, bone fracture, headache, and pharyngitis. See below for a comprehensive list of adverse effects.
When should thiazolidinediones be avoided?
Both the thiazolidinediones should be avoided for older adults with type II diabetes who have heart failure or are at risk for heart failure. Rosiglitazone should be avoided in older type II diabetic patients at risk for cardiovascular disease.
What are the contraindications of sulfonylureas?
Contraindications to the use of sulfonylureas include hypersensitivity to sulfonylureas and drugs that have similar structures (see earlier) and pregnancy. Caution should be exercised in cases of reduced renal or hepatic function. Patients with ketoacidosis should receive insulin, not an oral antihyperglycemic agent.
Who should not use acarbose?
Acarbose is not approved for use by anyone younger than 18 years old.
Can acarbose help me lose weight?
Conclusion: In obese individuals who undergo a hypocaloric diet and achieve a substantial loss of body weight, acarbose treatment provides only a very modest, not significant benefit to stabilise weight reduction. Thus, acarbose is not a useful adjunct to improve weight maintenance in obese subjects after weight loss.
Who should not take pioglitazone?
The risk is higher if you’re over 65 years old. If you already have heart failure, there’s a small chance that taking pioglitazone can make it worse. If you’re unusually short of breath, put on weight quickly or have swollen legs, feet or ankles (oedema), see your doctor straight away.
Does pioglitazone cause anxiety?
Your doctor may occasionally change your dose. Use the medicine exactly as directed. Pioglitazone is usually taken once daily, with or without food. You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky.
Are there any side effects to taking thiazolidinediones?
Conclusions: Common side effects associated with TZDs include edema, weight gain, macular edema and heart failure. Moreover, they may cause hypoglycemia when combined with other antidiabetic drugs as well as decrease hematocrit and hemoglobin levels.
Is the thiazolidinedione troglitazone safe to use?
Thiazolidinediones are usually well tolerated; however, their use may be associated with several adverse effects. The first TZD, troglitazone, was withdrawn from the market owing to serious hepatotoxicity. However, this does not seem to be the case with newer TZDs.
Why are there different side effects for TZDs?
Because TZDs target an important receptor that activates a variety of different genes, there have been varying side effects between different individual drugs within the class.
When to use thiazolidinedione in type 2 diabetes?
A thiazolidinedione treatment may be prescribed as a treatment for people with type 2 diabetes if metformin and either sulphonylureas or prandial glucose regulators are not tolerated or successful in lowering blood glucose levels sufficiently.