What class of antibiotic is aztreonam?
What class of antibiotic is aztreonam?
Aztreonam (azthreonam; SQ 26,776) is the first member of a new class of beta-lactam antibiotics, the monobactams. Aztreonam is selectively active against Gram-negative aerobic bacteria and inactive against Gram-positive bacteria.
Is aztreonam a beta-lactam antibiotic?
Aztreonam is a monobactam antibiotic that contains a betalactam ring. However, unlike other beta-lactam antibiotics, aztreonam does not contain a bicyclic-ring structure (6). To date, aztreonam has not demonstrated clinical cross-reactivity in penicillin-allergic patients (2, 8).
What class of drug is meropenem?
Meropenem injection is in a class of medications called antibiotics. It works by killing bacteria that cause infection. Antibiotics such as meropenem injection will not work for colds, flu, or other viral infections.
What is meropenem antibiotic category?
Uses. Meropenem is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic.
Is aztreonam a broad spectrum antibiotic?
Aztreonam exhibits potent and specific activity in vitro against a wide spectrum of gram-negative aerobic pathogens including Pseudomonas aeruginosa. It has no useful activity against gram-positive bacteria or anaerobes, but has very broad spectrum against gram-negative aerobes, including Pseudomonas aeruginosa.
What type of antibiotic is azactam?
AZACTAM® (aztreonam for injection, USP) contains the active ingredient aztreonam, a monobactam. It was originally isolated from Chromobacterium violaceum. It is a synthetic bactericidal antibiotic.
What are the contraindications of aztreonam?
Who should not take AZTREONAM?
- diarrhea from an infection with Clostridium difficile bacteria.
- liver problems.
- decreased kidney function.
What type of antibiotic is ceftriaxone?
Ceftriaxone is a cephalosporin (SEF a low spor in) antibiotic. Ceftriaxone is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as E. coli, pneumonia, or meningitis.
Is meropenem strong?
Meropenem (Merrem) is considered one of the stronger antibiotics. It works against many types of bacteria and treats severe or complicated infections when other antibiotics may not be enough. Keep in mind that “stronger” antibiotics are not always the best choice.
Does meropenem cause kidney damage?
Meropenem is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with renal impairment.
What is the other name for meropenem?
Meropenem, sold under the brandname Merrem among others, is an intravenous β-lactam antibiotic used to treat a variety of bacterial infections.
How is aztreonam used in the treatment of bacteria?
A review of its antibacterial activity, pharmacokinetic properties and therapeutic use Aztreonam (azthreonam; SQ 26,776) is the first member of a new class of beta-lactam antibiotics, the monobactams. Aztreonam is selectively active against Gram-negative aerobic bacteria and inactive against Gram-positive bacteria.
What is the active ingredient in aztreonam injection?
Aztreonam for Injection, USP contains the active ingredient Aztreonam, a monobactam. It was originally isolated from Chromobacterium violaceum. It is a synthetic bactericidal antibiotic.
Can you combine aztreonam with another antibiotic?
Where necessary, aztreonam and the standard drug have both been combined with another antibiotic active against Gram-positive and/or anaerobic bacteria.
Which is a better antibiotic aztreonam or cephalosporins?
Thus, with an antibacterial spectrum which differs from that of other antibiotics, aztreonam should be a useful alternative to aminoglycosides or ‘third generation’ cephalosporins in patients with proven or suspected serious Gram-negative infections. Publication types Clinical Trial Review