What disease is caused by Penicillium marneffei?
What disease is caused by Penicillium marneffei?
Penicillium marneffei is an emerging pathogenic fungus that can cause a fatal systemic mycosis in patients infected with human immunodeficiency virus (HIV).
What diseases can be caused by Talaromycosis Penicilliosis Marneffei?
In people with HIV, skin bumps due to talaromycosis usually have a small dent in the center. In people who do not have HIV, these bumps are more likely to appear smooth. Talaromycosis is also more likely to cause fever and swelling of the spleen in people who have HIV.
What is Penicilliosis?
Penicilliosis is an infection caused by Penicillium marneffei, a dimorphic fungus endemic to Southeast Asia and the southern part of China.(1) Rarely noted before the AIDS epidemic, P marneffei infections have become more prevalent in the endemic areas in conjunction with the AIDS epidemic.(2,3) Persons affected by …
What Penicillium species is considered a serious opportunistic pathogen causing infection?
Penicillium citrinum: Opportunistic pathogen or idle bystander? A case analysis with demonstration of galactomannan cross-reactivity.
How Penicilliosis infection is spread?
The pathogenesis of penicilliosis has been poorly studied. Though the disease can be localized, it is more likely to be disseminated in both normal and immunocompromised hosts. Infection is thought to occur through inhalation of the conidia or through cutaneous inoculation.
Where can I find a Penicillium marneffei infection?
Penicillium marneffei infection found in both immunocompetent and immunosuppressed patients. P marneffei found in Southeast Asia and southern China. Mold, septate hyphae 1.5-5 um in diameter. May be cultured from a variety of specimens including blood. Penicillium spp. other than P marneffei occur worldwide.
How to diagnose invasive disease other than P marneffei?
The diagnosis of invasive disease by Penicillium spp. other than P marneffei must be based on histologic evidence of tissue invasion and recovery of the organism from tissue culture.
When did Penicillium marneffei become known as Talaromycosis?
Penicillium marneffei was renamed Talaromyces marneffei in 2015, and the disease, which had been referred to as penicilliosis, is now called talaromycosis. For HIV-infected individuals, this systemic fungal infection was commonly diagnosed prior to the era of potent antiretroviral therapy (ART).
Can A P marneffei infection be granulomatous?
P marneffei infection in immunosuppressed patients can be granulomatous or necrotizing and is likely to disseminate.