What is GAZYVA used to treat?
What is GAZYVA used to treat?
Generic Name: obinutuzumab Obinutuzumab is used to treat certain types of blood cancer (such as chronic lymphocytic leukemia, follicular lymphoma). Obinutuzumab belongs to a class of drugs known as monoclonal antibodies. It works by stopping the growth of cancer cells.
How often is GAZYVA given?
GAZYVA is given for a total of 6 cycles, or rounds of treatment. Each cycle will last 28 days. Treatment occurs only on certain days of each cycle and that is usually followed by several weeks of rest and recovery. This means that most people will complete their GAZYVA treatment in about 6 months.
Is GAZYVA the same as Rituxan?
STOCKHOLM — Final results from the phase 3 CLL11 trial confirm the superiority of the newer anti-CD20 monoclonal antibody drug obinutuzumab (Gazyva) compared to the older agent rituximab (Rituxan); both agents are from the same manufacturer, Roche, which sponsored the study.
Is GAZYVA a chemo?
Gazyva™ is the trade name for the generic chemotherapy drug obinutuzumab. In some cases, health care professionals may use the generic name obinutuzumab when referring to the trade name Gazyva™. Drug Type: Gazyva™ is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.
How do you infuse GAZYVA?
Each dose of GAZYVA is 1000 mg, administered intravenously, with the exception of the first infusions in cycle 1, which are administered on day 1 (100 mg) and day 2 (900 mg). Day 1 100 mg Administer at 25 mg/hr over 4 hours. Do not increase the infusion rate.
Do you lose your hair with GAZYVA?
If you lose hair, you may lose it from your head, face, armpits, pubic area, chest, and/or legs. You may also notice your hair getting thin. While you are getting this drug in your vein (IV), you may have a reaction to the drug. Sometimes you may be given medication to stop or lessen these side effects.
Does Gazyva cause hair loss?
Hair loss may happen suddenly or gradually. If you lose hair, you may lose it from your head, face, armpits, pubic area, chest, and/or legs. You may also notice your hair getting thin. While you are getting this drug in your vein (IV), you may have a reaction to the drug.
How long is a Gazyva infusion?
Administer at 25 mg/hr over 4 hours. Do not increase the infusion rate. The Day 1 dose for GAZYVA is 100 mg in 100 mL.
What is the difference between rituximab and Obinutuzumab?
Obinutuzumab is a type II antibody, unlike rituximab, which is a type I antibody. These classifications are based on the way the antibodies bind to CD20.
Is chlorambucil a chemotherapy?
Drug Type: Chlorambucil is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “alkylating agent.” (For more detail, see “How this drug works” section below).
What is the cost of GAZYVA?
Cost of Gazyva is $41,300 for one 6-month course of treatment. Additional information can be found at www.gazyva.com.
Is Obinutuzumab and immunotherapy?
Immunotherapy with monoclonal antibodies, such as obinutuzumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving bendamustine, obinutuzumab, and venetoclax may work better in treating patients with mantle cell lymphoma.
How to report side effects of Gazyva by prescription?
GAZYVA is available by prescription only. You may report side effects to the FDA at (800) FDA-1088, or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. Please see the accompanying full Prescribing Information, including BOXED WARNINGS, for additional Important Safety Information.
How is Gazyva used to treat follicular lymphoma?
GAZYVA ® (obinutuzumab) is a prescription medicine used with the chemotherapy drug, bendamustine, followed by GAZYVA alone for follicular lymphoma (FL) in adults who did not respond to a rituximab-containing regimen, or whose FL returned after such treatment.
Can you get thrombocytopenia while taking Gazyva?
While you are taking GAZYVA, your doctor will do blood work to check your platelet count. Severe and life-threatening thrombocytopenia can develop during treatment with GAZYVA. Fatal bleeding events have occurred in patients treated with GAZYVA.
How long can neutropenia last after taking Gazyva?
Severe and life-threatening neutropenia can develop during or after treatment with GAZYVA. Some cases of neutropenia can last for more than one month. If your white blood cell count is low, your doctor may prescribe medication to help prevent infections Low Platelet Count: Platelets help stop bleeding or blood loss.