What is sibutramine hydrochloride monohydrate?
What is sibutramine hydrochloride monohydrate?
What Is Meridia? Meridia (sibutramine hydrochloride or sibutramine hydrochloride monohydrate) assists with weight-loss by altering neurotransmitters within the brain and is used along with a low-calorie diet to help people with obesity lose weight.
Is sibutramine legal anywhere?
It has been sold under a variety of brand names including Reductil, Meridia, Siredia, and Sibutrex. It is classified as a Schedule IV controlled substance in the United States….Sibutramine.
| Clinical data | |
|---|---|
| Routes of administration | Oral (capsules) |
| ATC code | A08AA10 (WHO) |
| Legal status | |
| Legal status | US : Schedule IV |
Is sibutramine available in the US?
Sibutramine is no longer available in the U.S. because of the risk of serious cardiovascular problems in some people who take it. Sibutramine is indicated for the management of obesity, including weight loss and maintenance of weight loss, and should be used in conjunction with a reduced calorie diet.
How do you take sibutramine hydrochloride?
Sibutramine can be taken with or without food. You should lose at least 4 pounds during the first 4 weeks of taking sibutramine and eating a low calorie diet. Tell your doctor if you do not lose at least 4 pounds after taking the medication for 4 weeks. Your blood pressure and pulse will need to be checked often.
What type of drug is sibutramine?
Sibutramine is a norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity. Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity.
How effective is sibutramine?
At 1 year, adults receiving sibutramine, 10 to 15 mg/d, lost an average of 4.5 kg (9.8 pounds) more than adults receiving placebo. Adults taking sibutramine for 1 year are 19% to 34% more likely to achieve 5% weight loss and 12% to 31% more likely to achieve 10% weight loss than those taking placebo.
What kind of drug is sibutramine?
Sibutramine is an anti-obesity drug that produces short-term and modest body weight reductions mainly due to its appetite-suppressing effect. Despite being a useful drug in obesity treatment, awareness about the loss of effectiveness and detrimental side effects of sibutramine has recently emerged.
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