What is the average age for DCIS?
What is the average age for DCIS?
The average age at DCIS diagnosis was 53.8, and the women were followed for an average of 7.5 years. DCIS is often described as a “pre-invasive neoplastic lesion that is not lethal in itself,” according to the authors, but “the results of the present study suggest that …
Does DCIS shorten life expectancy?
Generally, patients diagnosed with DCIS have an excellent long-term breast-cancer-specific survival of around 98% after 10 years of follow-up24–27 and a normal life expectancy.
How quickly can DCIS become invasive?
It assumes that all breast carcinomas begin as DCIS and take 9 years to go from a single cell to an invasive lesion for the slowest growing lesions, 6 years for intermediate growing DCIS lesions, and 3 years for fast-growing DCIS lesions.
What percentage of DCIS becomes cancer?
” DCIS rarely leads to death from breast cancer – approximately 11 out of 100 women treated by lumpectomy only go on to develop invasive cancer within eight years of the initial diagnosis of DCIS, and only 1 to 2 percent of women die of breast cancer within 10 years of diagnosis.
How quickly does DCIS progress?
Grade 1 DCIS is almost always ER and PR positive and is a very slow growing form of cancer. It can take years, even decades, to see progression of the disease. In some cases, it may take such a long time to spread beyond the breast duct that it is not an event that will happen during a person’s lifetime.
How fast does high grade DCIS progress?
The largest studies on the natural history of DCIS suggest that more than 50% of patients with high-grade DCIS have the potential to progress to an invasive carcinoma in less than 5 years if left untreated, while low-grade DCIS has a similar progression but in a small percentage of patients (35–50%) and in a more …
Should I have a mastectomy for DCIS?
Mastectomy involves removal of the whole breast and is usually recommended if the DCIS affects a large area of the breast, if it has not been possible to get a clear area of normal tissue around the DCIS by wide local excision, or if there is more than one area of DCIS.
What is best treatment for high-grade DCIS?
Standard treatment options for DCIS include: Lumpectomy followed by radiation therapy: This is the most common treatment for DCIS. Lumpectomy is sometimes called breast-conserving treatment because most of the breast is saved. Mastectomy: Mastectomy, or removal of the breast, is recommended in some cases.
What stage is high grade DCIS?
DCIS that is high grade, is nuclear grade 3, or has a high mitotic rate is more likely to come back (recur) after it is removed with surgery. DCIS that is low grade, is nuclear grade 1, or has a low mitotic rate is less likely to come back after surgery.
Is DCIS 100 curable?
But DCIS is nearly 100 percent curable. Typically, the treatment is a small operation called lumpectomy, often but not always followed by radiation to the area.
What are the chances of DCIS coming back?
When you have had DCIS, you are at higher risk for the cancer coming back or for developing a new breast cancer than a person who has never had breast cancer before. Most recurrences happen within the 5 to 10 years after initial diagnosis. The chances of a recurrence are under 30%.
What is the survival rate for high grade DCIS?
In spite of the unknown, the overall prognosis for DCIS is excellent with appropriate surgical and oncologic management (approximately 98% long-term survival). DCIS is typically treated with wide surgical resection with or without radiation therapy; there is an evolving role for hormonal therapy.
How are older women diagnosed with DCIS or early-stage disease?
Older Women Diagnosed With DCIS or Early-Stage Disease Have Excellent Prognosis. Women diagnosed with DCIS have very good prognoses. Ten years after DCIS diagnosis, 98% to 99% of women will be alive. Based on this good prognosis, DCIS usually is treated by lumpectomy followed by radiation therapy.
What’s the survival rate for women with DCIS?
The researchers projected 10-year survival rates for all the women and compared the projected survival rates of women diagnosed with DCIS or invasive breast cancer to the rates of women not diagnosed with breast cancer. Women diagnosed with DCIS were 10% more likely to be alive after 10 years compared to women not diagnosed with breast cancer.
Can you get breast cancer if you have DCIS?
DCIS stays inside the breast milk duct. DCIS can be large or small, but it doesn’t spread outside the milk duct into the surrounding normal breast tissue or into the lymph nodes or other organs. Still, a woman diagnosed with DCIS is at higher risk of developing invasive breast cancer in the same breast compared to someone who hasn’t had DCIS.
What’s the difference between low grade and moderate grade DCIS?
Low Grade DCIS: This may also be called Nuclear Grade 1 or ‘low mitotic rate’. These cancer cells look very similar to normal breast cells and are less likely to recur after surgery. Moderate Grade DCIS: This grade is also called Nuclear Grade 2 or ‘intermediate mitotic rate’. This grade of DCIS tends to fall between low grade and high grade.