Q&A

What is the normal value of anti-HBs?

What is the normal value of anti-HBs?

For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.

What does anti-HBs positive indicate?

I. ■ Anti-HBs [sometimes written as HBsAb] (antibody to hepatitis B surface antigen): when this is “positive” or “reactive,” it means the person is immune to hepatitis B infec- tion, either from vaccination or from past infection. (This test is not done routinely by most blood banks on donated blood.)

What is anti HBe non reactive?

An anti-HBe test that is non-reactive (negative) may mean the infection is very recent and viral replication has not yet peaked.

What is Anticorps HBs?

Anti-HBs is an antibody produced by the body against the surface antigens of the hepatitis B virus (HBsAg). The appearance of anti-HBs in the serum follows the disappearance of HBsAg. In most individuals, anti-HBs persists for life and provides long-term immunity.

What if anti-HBe is reactive?

When the anti-HBe is also reactive, this means the individual is in the process of healing and is less contagious. A non-reactive HBeAg result (with a reactive anti-HBe result) in a person with hepatitis B indicates that the infection is in its initial phase, before peak replication of the virus.

What is HBcAb negative?

A negative HBcAb test result is reported as HBV-negative, and a positive result is followed by testing for HBsAg and, if this result is negative, HBsAb. HBsAg-positive sera are tested for hepatitis B e antigen (HBeAg) and hepatitis B e antibody (HBeAb).

How did I get hepatitis A?

Hepatitis A can be spread from close, personal contact with an infected person, such as through certain types of sexual contact (like oral-anal sex), caring for someone who is ill, or using drugs with others. Hepatitis A is very contagious, and people can even spread the virus before they feel sick.

What does it mean to have anti Hbs antibody?

antibody (anti-HBs): The presence of anti-HBs is generally interpreted as indicating recovery and immunity from hepatitis B virus infection. Anti-HBs also develops in a person who has been successfully vaccinated against hepatitis B. Total hepatitis B core

What does anti-HBc stand for in hepatitis B?

immunity from hepatitis B virus infection. Anti-HBs also develops in a person who has been successfully vaccinated against hepatitis B. Total hepatitis B core antibody (anti-HBc): Appears at the onset of symptoms in acute hepatitis B and persists for life. The presence of anti-HBc indicates previous or ongoing infection with hepatitis B virus in an

Can you get HBV without an anti-HBs?

HBV “escape” mutants in which the HBsAg is altered can result in HBV infections without detectable anti-HBs. Typical sequence of serologic markers in patients with acute HBV infection with resolution of symptoms (Horvat, R. T., and Tegtmeier, G. E. 2007).

How many mIU / ml of anti-HBs is protective?

For determination of immunity the World Health Organization (WHO) recognizes a level of 10 mIU/ml of anti-HBs as protective. See Special Instructions for PHL recommended diagnostic approach to hepatitis. Curry, M. P., and Chopra, S. 2010.