Which antihypertensive medication is more effective in African-Americans?
Which antihypertensive medication is more effective in African-Americans?
In the text of the guideline, mentions that diuretics should be the agent of first choice for blacks with hypertension because of their proven effectiveness in clinical trials. For whites, beta-blockers are also an option for first line therapy. Mono-therapy with beta-blockers or ACE-Is is less effective in blacks.
Does ethnicity play a role in hypertension?
Racial/ethnic minority adults have higher rates of hypertension than non-Hispanic white adults. We examined the prevalence of hypertension among Hispanic and Asian subgroups in New York City.
What race is most affected by hypertension?
Rates of High Blood Pressure Control Vary by Sex and Race High blood pressure is more common in non-Hispanic black adults (54%) than in non-Hispanic white adults (46%), non-Hispanic Asian adults (39%), or Hispanic adults (36%).
Does patient’s cultural origin play a role in the selection of antihypertensive drugs?
These new studies have unequivocally shown that there are clinically important differences in BP-lowering response to both first- and second-line antihypertensive agents among hypertensive patients from different ethnic groups.
Why do ACE inhibitors not work on African Americans?
The implication that there are inherent biological differences between black people and members of other races has entered blood pressure medication guidance. Black people are labelled “low-renin responders” so are less likely to respond to ACE inhibitors.
How does race cause hypertension?
Answer: Ethnicity or sometimes referred to as race may affect one’s risk of developing high blood pressure in that we do see differences in levels of blood pressure and the incidence and prevalence of high blood pressure in certain ethnic groups such as African-Americans. We see a higher rate of high blood pressure.
Do Asians suffer from hypertension?
Their ongoing study, known as Masala, for Mediators of Atherosclerosis in South Asians Living in America, has found that South Asians tend to develop high blood pressure, high triglycerides, abnormal cholesterol and Type 2 diabetes at lower body weights than other groups.
What is lowest blood pressure before death?
When an individual is approaching death, the systolic blood pressure will typically drop below 95mm Hg. However, this number can vary greatly as some individuals will always run low.
Why can’t African Americans use ACE inhibitors?
Angiotensin converting enzyme (ACE) inhibitors have been avoided as an initial therapeutic option in the treatment of hypertension in African-Americans. A major reason for this has been the widespread perception of clinicians that these agents have poor blood pressure (BP) lowering efficacy in this population.
Are ARBs effective in African Americans?
More recently, studies with angiotensin receptor blockers (ARBs) have shown blood pressure (BP) response in African Americans that is less than that in whites,[10,11] but this difference was eliminated when ARBs were combined with low-dose diuretics.
Are there racial disparities in blood pressure treatment?
A greater proportion of blood pressure control among those treated for hypertension has been observed among Mexican-Americans (74%) and whites (75%) compared with blacks (62%) ( 6 ).
How does race and ethnicity affect drug use?
The impact of race/ethnicity on drug disposition is understood to some extent by clinicians when making treatment decisions. I’ve seen clinicians consider this when deciding on whether or not to use an ACE inhibitor to treat hypertension, for example.
Who are more likely to have hypertension Black or white?
The 1960s Charleston Heart Study and other cohort studies show higher prevalence of hypertension among black participants than among white participants (5,6).
Are there racial / ethnic disparities in health care?
Finally, NHANES examination response rates ranged from 75% to 77%. Racial/ethnic disparities exist in blood pressure, awareness, treatment, and control, with Mexican-Americans having a lower awareness and treatment of hypertension, as well as less health-care coverage, compared with blacks and whites.