Which are antihyperlipidemic agents?
Which are antihyperlipidemic agents?
The six HMG-CoA reductase inhibitors (statins) are atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor, Altocor), pravastatin (Pravachol), rosuvastatin (Crestor), and simvastatin (Zocor). All are contraindicated in pregnancy (risk factor X).
Why are antihyperlipidemic drugs used?
Antihyperlipidemic agents promote reduction of lipid levels in the blood. Some antihyperlipidemic agents aim to lower the levels of low-density lipoprotein (LDL) cholesterol, some reduce triglyceride levels, and some help raise the high-density lipoprotein (HDL) cholesterol.
What are Antilipemic drugs used for?
These medications usually lower low-density lipoprotein (LDL) cholesterol levels. In addition, they sometimes lower triglyceride (TG) levels and may modestly elevate high-density lipoprotein (HDL) cholesterol levels.
What class of drugs are Antilipemic?
The medications for dyslipidemia can be grouped into five categories: fibrates, bile acid resins, hydroxymethylglutaryl co-enzyme A (HMG-CoA) reductase inhibitors (known collectively as statins), proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and miscellaneous agents.
What is an example of Antilipemic?
Seven statins are available in the United States: lovastatin (Mevacor: 1987), pravastatin (Pravachol: 1991), simvastatin (Zocor: 1991), fluvastatin (Lescol: 1993), atorvastatin (Lipitor: 1996), rosuvastatin (Crestor: 2003) and pitavastatin (Levalo: 2009).
How fast do fibrates work?
Takes about a week for levels to stabilize. May take several weeks before effects on cholesterol and triglycerides levels are apparent. Fenofibrate lowers total cholesterol by 9 to 13%, VLDL cholesterol by 44 to 49%, triglycerides by 46 to 54%, and apolipoprotein B (Apo B).
What medicines are fibrates?
Fibrate drugs, such as gemfibrozil (Lopid) and fenofibrate (TriCor), are undoubtedly the best tools to address the condition characterized by high triglycerides, low high-density lipoprotein (HDL), and small dense low-density lipoprotein (LDL) (atherogenic dyslipidemia), but the most recent guidelines from both the …
Which is the best description of an antihyperlipidemic drug?
HMG-CoA. Hypolipidemic agents, or antihyperlipidemic agents, are a diverse group of pharmaceuticals that are used in the treatment of high levels of fats (lipids), such as cholesterol, in the blood (hyperlipidemia). They are called lipid-lowering drugs .
Which is the best classification of lipid lowering drugs?
HMG-CoA. Hypolipidemic agents, or antihyperlipidemic agents, are a diverse group of pharmaceuticals that are used in the treatment of high levels of fats (lipids), such as cholesterol, in the blood (hyperlipidemia). They are called lipid-lowering drugs . Contents. 1 Classes. Established. 2 Research; 3 References; 4 See also.
How are hyperlipidemic drugs different from other drugs?
These classes differ nottreat hyperlipidemia. These classes differ not only in theironly in their mechanism of actionmechanism of action but also inbut also in the type of lipid reduction and the magnitudethe type of lipid reduction and the magnitude ofof the reduction.the reduction. 17.
Which is the most effective treatment for combined hyperlipidemia?
Therapeutic uses Hypertriglyceridemia the most effective in reduction TGs – combined hyperlipidemia type III if statins are contraindicated. Their half-lives range from 1. Niacin is administered orally. Thus, it is important to evaluate INR Contraindications: Colesevelam Colestilan Colestipol Colestyramine Colextran.