Can praziquantel be used on humans?
Can praziquantel be used on humans?
Praziquantel is a broad-spectrum, highly efficacious and safe, anthelmintic against trematode and cestode infections in humans and animals.
How much praziquantel do humans take?
The dose is 25 milligrams (mg) per kilogram (kg) of body weight taken 3 times a day for 1 day only. Each dose should be at least 4 hours apart and not more than 6 hours apart. Children younger than 1 year of age—Use and dose must be determined by the doctor.
How do you take praziquantel 600 mg?
Take this medication by mouth with a meal as directed by your doctor, usually 3 times a day (4 to 6 hours apart) for 1 day. Quickly swallow the tablets or tablet segments with a full glass of water (8 ounces or 240 milliliters).
What are the side effects of praziquantel?
Praziquantel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- not feeling well.
- headache.
- dizziness.
- stomach pain.
- nausea.
- fever.
- itching.
What happens after you take praziquantel?
Side Effects Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites.
How long is praziquantel effective?
An interesting quirk of praziquantel is that it is relatively ineffective against juvenile schistosomes. While initially effective, effectiveness against schistosomes decreases until it reaches a minimum at 3-4 weeks. Effectiveness then increases again until it is once again fully effective at 6-7 weeks.
Is praziquantel a chemotherapy?
Chemotherapy with the pyrazinoisoquinoline praziquantel has been demonstrated to be effective in decreasing morbidity in schistosomiasis (19) and is currently the most widely accepted method for the control of the disease. The drug is safe and has a high efficacy against both trematodes and cestodes (9, 11).
How effective is praziquantel?
After 4 weeks of administration of praziquantel, the cure rate was 86.9% with egg reduction rate of 78.3%. Effectiveness of the drug was not statistically associated with sex, age group, and pre-treatment intensity of infection.
How often can I use praziquantel?
The dose is 20 milligrams (mg) per kilogram (kg) of body weight taken 3 times a day for 1 day only. Each dose should be at least 4 hours apart and not more than 6 hours apart. Children younger than 1 year of age—Use and dose must be determined by the doctor.
How long does it take for praziquantel to take effect?
This medication should take effect within 1 to 2 hours; however, effects may not be noted outwardly and therefore laboratory tests may need to be done to evaluate this medication’s effectiveness.
What do you need to know about praziquantel?
Praziquantel is a prescription drug used as anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body. Praziquantel is used to treat infections caused by Schistosoma worms, which enter the body through skin that has come into contact…
How is praziquantel used to treat schistosomiasis?
As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. Paragonimiasis caused by infection with lung flukes, mostly of the species Paragonimus westermani.
How is praziquantel used to treat liver flukes?
Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish.
What to do if you overdose on praziquantel?
In case of overdose, get medical help or contact a Poison Control Center immediately. Treatment with rifampin can be restarted 1 day after completion of praziquantel treatment. See “What Are Side Effects Associated with Using Praziquantel?”