What is the purpose using yttrium-90 which is a beta emitter?
What is the purpose using yttrium-90 which is a beta emitter?
The rare-earth lanthanide, Yttrium-90 (90Y), is almost exclusively a high-energy beta-particle (i.e., electron or β−) emitting radionuclide used for radiotherapy with a maximum particle energy of 2.28 MeV (average energy of 0.94 MeV) that allows for high dose deposition with an average and maximum soft tissue …
Why is yttrium-90 used in radiotherapy?
In Y-90 radiotherapy, millions of tiny radioactive beads are injected directly into the arteries that supply blood to your tumor. These beads will stay in the blood vessels around your tumor(s). This allows very strong radiation to reach the tumors directly.
How long does Y90 last?
Because radioactive microspheres are delivered through the hepatic artery, they reach the tumor very directly while sparing most of the healthy liver tissue. The radiation from yttrium-90 continually decreases over a two-week period and disappears after 30 days.
Is yttrium-90 natural or synthetic?
Yttrium is almost always found in combination with lanthanide elements in rare-earth minerals, and is never found in nature as a free element. Y is the only stable isotope, and the only isotope found in the Earth’s crust.
Is the Y90 safe?
Y90 is a relatively new, safe, and highly successful treatment for cancer in the liver that targets tumors with a high dose of radiation without affecting other, healthy parts of the body.
Where does yttrium-90 come from?
Yttrium-90 is produced by the nuclear decay of strontium-90 which has a half-life of nearly 29 years and is a fission product of uranium used in nuclear reactors. As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation.
Is yttrium toxic to humans?
Water soluble compounds of yttrium are considered mildly toxic, while its insoluble compounds are non-toxic. Exposure to yttrium compounds in humans may cause lung disease.
Why is it called yttrium?
Yttrium is named after Ytterby, Sweden.
Does Y90 make you sick?
You may feel more tired than usual and tire more easily for up to 3 weeks after the procedure. You may feel sick to your stomach and not feel like eating for several days. You will be given a prescription for medicine to control the nausea. You may lose some weight before you feel like eating again.
What is the half life of yttrium 90?
Yttrium-90 (90 Y) is a beta (electron) emitter with an average energy of 0.9267 MeV and a half-life of 2.67 days. Over 90% of emitted energy is absorbed within 5.3mm and the maximum range of emitted electons is 11mm. Y-90 is most commonly used in radiation therapy as the source in microsphere liver treatments.
How many neutrons are in the yttrium 90 atom?
General Symbol 90 Y Names yttrium-90, Y-90 Protons 39 Neutrons 51
What kind of cancer does yttrium 90 y treat?
90 Y plays a significant role in the treatment of hepatocellular carcinoma (HCC), leukemia, and lymphoma, although it has the potential to treat a range of tumors.
What was the median response time for yttrium-90?
Median response duration was 28.1 months (range, 10.5-80.3+ months). Median TTP was 29.3 months (range, 12.1-81.5+ months). In patients with ongoing response, median TTP was 53.9 months (range, 49-82+ months). CONCLUSIONS: (90)Y ibritumomab tiuxetan produces durable long-term responses in patients with relapsed/refractory B-cell NHL.